Type A behavior and ischaemic heart disease.

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Type A behaviour and ischaemic heart disease.

It is a common medical belief that psychosocial factors, in some form or another, contribute to the risk of developing ischaemic heart disease (IHD). Anecdotal evidence comes from many of the great figures of medical history. William Harvey described a coronary patient whose illness was the result of 'anger and indignation which he yet communicated to no one' (Leibowitz, 1970). John Hunter's an...

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Metabolomics and ischaemic heart disease.

Ischaemic heart disease accounts for nearly half of the global cardiovascular disease burden. Aetiologies relating to heart disease are complex, but dyslipidaemia, oxidative stress and inflammation are cardinal features. Despite preventative measures and advancements in treatment regimens with lipid-lowering agents, the high prevalence of heart disease and the residual risk of recurrent events ...

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Thrombosis and ischaemic heart disease.

The overwhelming dominance of the lipid hypothesis for atheroma has obscured the compelling evidence-some of it of many years standing' but some that is more recent2 3 -that both platelets and the coagulation system also contribute to the lesion. There is much epidemiological evidence4 5 of some other process besides atherogenesis to account for the clinical manifestations of coronary artery di...

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Ischaemic heart disease.

There can be no truly objective frequency estimate of the susceptibility of the population to ischaemic heart disease: everybody has some degree of susceptibility. The disease kills 1 in 4 of the population, and 1 man in 10 dies of ischaemic heart disease before 65 years of age. The major burden is mortality, though there is often some degree of impairment among survivors of acute attacks. It i...

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Pre-existing ischaemic heart disease and ischaemic heart disease mortality in women compared with men.

BACKGROUND In all 8353 women and 7058 men aged 45-64 took part in the Renfrew/Paisley survey in 1972-1976. They formed a prospective cohort study of a general population in the West of Scotland; an area with high ischaemic heart disease (IHD) mortality rates. The objective of this study was to investigate three indicators of pre-existing IHD and determine how they predicted subsequent IHD morta...

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ژورنال

عنوان ژورنال: BMJ

سال: 1987

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.295.6602.851-c